Dr. Feng Bian
Pfizer
Sr Director/Emerging Science Lead-ChinaFabio Bianco
Neuro-Zone, since 13 years, supports drug discovery, drug repurposing and research projects in the fields of inflammation and age-related pathologies.
In particular, we have developed pathology-specific platforms to generate rapid and informative data on efficacy, toxicity, metabolism and mechanism of action, supported by proprietary technologies such as MicroTISSUE (dissecting microenvironment-cell interaction in complex inflammatory scenarios) or MITOS (a comprehensive analytical platform for quantitative analysis of mitochondrial function ).
Our approach enables effective selection and ranking of the most promising candidates per indication.
Moreover, we profile candidates at different level of complexity starting from:
a) pharmacology profiling (GPCR; Ion Channel receptors)
b) identification of biochemical pathways responsible for therapeutic efficacy (transcriptomics)
c) disease modified barrier permeability (BBB and endothelial)
NeuroZone
PresidentDr. Petter Bjorquist
VERIGRAFT AB
CEODr. Jenny Blamey
Swissaustral
Chief Scientific OfficerRichard Brand
20/20 GeneSystems, headquartered in Rockville, Maryland (outside of Washington, D.C.), is a revenue stage diagnostics company that uses machine learning algorithms to greatly improve the accuracy of laboratory tests for the early detection of cancer and other diseases. In the most recent calendar year our revenues grew to over $2 million aided by several COVID-19 tests that we are successfully commercializing.
Our multi-cancer early detection blood test (www.OneTest.Ai) measures tumor antigens and uses a machine learning algorithm powered by outcome data from over 230,000 individuals tested in real-world screening settings. OneTest is a highly accessible and affordable pre-test that can be followed up with more expensive and specific circulating tumor DNA tests such as those being developed by Grail and Thrive Earlier Detection. (Those companies were recently acquired for $8 billion and $2 billion respectively.)
20/20’s institutional investors include Ping An, one of the largest digital health and insurance companies in China, and several well-regarded American funds. We are working to an initial public offering in 2021 and are now lining up IPO “crossover” investors.
20/20 GeneSystems, Inc.
CFODr. Ross Breckenridge
The mechanism of action of our lead drug, Ag5, targets cancer cells generating high levels of Reactive Oxygen Species (ROS) via a synthetic lethality mechanism. High ROS tumours are, in general, untreatable. This group of cancers includes KRAS- and MYC-mutation driven cancers, which comprise above 30% of all cancer cases. leading to more than 1 million deaths worldwide every year. Treatment options for this group of cancers are extremely limited. We expect that our lead compound will define a new treatment paradigm across existing cancer categories. We have robust biomarkers to drive clinical development and links to world leading cancer centres in Europe and Asia.
We have a follow-on compound and a pipeline of innovative molecules addressing both cancer and non-cancerous conditions.
We are raising a series A round which will allow us to gain clinical proof of concept. Our mission is to restore hope to patients and their families.