Astrocyte Pharmaceuticals United States

Astrocyte Pharmaceuticals is a preclinical CNS drug development company advancing breakthrough therapeutic agents for treating brain injury patients. Astrocyte is developing the proprietary small molecule pharmaceutical agent AST-004 for acute administration to patients who have suffered a stroke, TBI, or concussion. This product would be administered by intravenous injection by emergency responders or a medical professional within 24 hours of injury to limit neuronal damage and cell death. Our approach at Astrocyte Pharmaceuticals differs significantly from historical neuroprotective attempts as we focus on a non-neuronal cell type, the astrocyte, which is the most common cell type in the human brain and has only recently received broader attention as an important cellular target for therapeutic research. The company recently demonstrated AST-004's significant efficacy in an NHP stroke study that mirrors the planned Phase 2 clinical study, and large safety margins in GLP toxicology studies. The company completed its Series A financing in Q4 2020.

Company Size (Fulltime employees)
Year of foundation
2014
Partnering Objectives
Please specify your partnering goal
Explore out-licensing of China commercialization rights
Headquartner in China
Assets Information 1
AST-004|Adenosine A3 receptor agonist|stroke, TBI, concussion, Alzheimer's, pain, etc.|USA; China and other countries pending
Biotech/Pharma Asset Stage
Dr. William Korinek
Dr. William Korinek
LinkedIn logo CEO 
Functionality

Atropos Therapeutics United States

senescence company
Company Size (Fulltime employees)
Please specify your partnering goal
Seed capital
Headquartner in China
Biotech/Pharma Category
Mr. Ethan Than
Head of BD 
Functionality

Aventurine Capital Management, LLC United States

We bring foundational science and commercial viability together for social and market impact.

We provide a human innovation ecosystem offering commercially focused support for inventors.

DEEP TECH FUNDING REINVENTED WITH SCIENCE, FOR SCIENCE

6 practice areas: AI, Robotics, Life Science, Quantum Computing, Energy, Secure Platforms & Networks
Company Size (Fulltime employees)
Please specify your partnering goal
Strategic collaboration
Headquartner in China
Mr. Avery Lu
Investment Research Lead 
Functionality

BALINBAC THERAPEUTICS, INC. United States

BalinBac Therapeutics, Inc. is a clinical stage biopharmaceutical development company headquartered in Princeton, New Jersey, focused on rapidly bringing both repurposed and new antivirals and antibiotics to market. BalinBac started working on coronavirus drug solutions in January 2020 when the team predicted the impact of the COVID-19 pandemic.

Our scientists and therapeutics development executives have a wealth of working knowledge in the pharmaceutical industry and have a track record of successfully bringing key antiviral and antibacterial drugs to market. We know how to rapidly get drugs to patients and what it takes to get this work done quickly.
Website:
www.balinbac.com
Year of foundation
2014
Headquartner in China
Assets Information 1
BalinBac has a lead clinical stage drug (phase 2/3) repurposed candidate, BB-708, with validated COVID-19 suppressing antiviral activity utilizing multiple recognized mechanisms of action. This SARS-CoV-2 activity has been demonstrated in a number of labs at a drugable micromolar level in human lung cell NHBE and Calu-3 cell line viral neutralization assays. BB-708 is a drug product in a unique inhaled drug delivery system that will stop viral replication of SARS-CoV-2. BalinBac’s multiple MOA anti-coronavirus drugs and inhaled delivery system provides a platform for repurposed therapeutics that will now have 20-year composition of matter patents as NCEs through BalinBac’s proprietary medicinal chemistry. This platform will be extended to other therapeutic areas after addressing the huge unmet need of the COVID-19 pandemic. We are seeking research collaboration and option agreements with big pharma and generic companies and are raising super-angel money to finance some small contributing studies relating to the formulation and for some general operating administrative expenses. We will be delivering the drugs to outpatients via electronic cigarettes in free base form and after this program enters the clinic will be developing a new device for hospital inpatient administration. We would be happy to talk to you about collaboration agreements and early investment.
Biotech/Pharma Asset Stage
Mr John Gregg
Mr John Gregg
CEO 
Functionality

BioPegasus, LLC United States

BioPegasus, LLC specializes in a cost-effective and robust post-proteomics and post-protein and peptide array technology biomarker and target discovery technology platform. This proprietary platform is unique and transformative, allowing systematic, thorough and unambiguous discovery, identification and isolation of tissue-specific and disease-specific autoantigens and key disease drivers/proteins and their genes, and disease-specific antibodies in order to solve some most challenging problems of our time. It aims to accelerate novel therapeutic and diagnostic development for some devastating diseases to improve our health and quality of life. These diseases include autoimmune diseases, cancer, and, in particular, Alzheimer’s disease.

BioPegasus' technology platform provides a revolutionary tool for systematical and thorough studying novel molecular interactions and mechanism of actions with any molecule of interest. The platform can be used to provide contract services with royalty payment potential to research institutions and companies in IVD, biotech and pharma sectors. The technology can also be packaged into commercial product(s) with a user manual for sale in the market world-wide.

BioPegasus currently is operated by its founder looking for an investor(s), partner(s), and sponsor(s)/client(s) or any form of collaboration/interest.

Website:
not available
Company Size (Fulltime employees)
Year of foundation
2006
Please specify your partnering goal
1) Seeking investment(s) for developing cost-effective and minimally invasive blood antibody biomarker tests for Alzheimer’s disease diagnosis and early detection (a 3-year project); and/or 2) Looking for any interested party(ies) to work together.
Headquartner in China
Assets Information 1
biomarker and target discovery technology platform|||
Biotech/Pharma Asset Stage
Your Research Tool and Service name
A unique and transformative λ phage cDNA expression library construction and screening (not phage display). A cost-effective and robust novel biomarker and target discovery technology platform for novel diagnostic and therapeutic development.
Service Description
BioPegasus' technology platform provides a revolutionary tool for systematically and thoroughly studying novel molecular interactions and mechanism of actions with any molecule of interest and allowing unambiguous discovery, identification and isolation of tissue-specific and disease-specific autoantigens and key disease drivers/proteins and their genes, and disease-specific antibodies in order to solve some most challenging problems of our time in novel diagnostic and therapeutic development.
Target client type
1) As diagnostic and early detection tests for Alzheimer's disease: general population for early detection (POCT, age 50 years and better) and patients for severity and diagnosis (lab tests); 2) As a research tool: client types include research institutions and diagnostic IVD, biotech and pharma companies
Slides Deck
(pdf, 957.61KB)
Dr. Tianlin Ma
Founder 
Functionality

Biostage, Inc. United States

Biostage is a biotechnology company developing bioengineered organ implants to treat congenital defects, cancers and other life-threatening conditions of the esophagus, bronchus and trachea.

The company’s novel Cellframe™ technology is engineered to stimulate the body’s signaling pathways and natural healing process to regenerate and restore organ function. Our Cellframe technology is based on over 20 years of scientific progress in the fields of tissue engineering, cell biology and material science. Cellframe technology combines the best attributes of a synthetic scaffold with tissue engineering and cell biology to create what may be a revolutionary method of addressing organ damage.

Biostage has been developing its new generation of organ implants as a platform capable of being used in the esophagus and main airways (trachea and bronchi). The current platform, based on our Cellframe technology, represents a complete re-engineering of our earlier organ scaffold and cell technology to better stimulate the regenerative properties of each of these organs. Biostage’s Cellframe technology platform is used to create organ specific Cellspan implants. Recent large animal data showed promising results as our Cellframe technology applied to the esophagus achieved the regeneration of esophageal tissue.
Website:
www.biostage.com
Company Size (Fulltime employees)
Please specify your partnering goal
Fund raising, invest,
Headquartner in China
Biotech/Pharma Category
Mr. Shunfu Hu
VP of Business Development and Operations 
Functionality

BioValleyCHINA Ventures United States

Assist Consultation, Assistance, Service
• Identify Distribution Opportunities, Partners, Joint Ventures
• Guidance for Product Registration (SFDA), Regulatory Issues
• Intellectual Property Assessment
• Develop Successful Business Strategy
• Marketing/Analysis
• Manufacturing/Sourcing
• Investment Advisory

Paul DeRidder
President 
Functionality

Bioxytran/Pharmalectin United States

Pharmalectin is working on the end-to-end solution for COVID-19 mild to severe cases and treatment for organ damage caused by the virus. The company has developed a novel method designed to reduce the viral load and modulate the immune system using a galectin inhibitor.

Academic study on a small number of patients with the first drug candidate had positive results. The viral load was reduced to zero in all mild/moderate patient after a few days. The drug is not toxic and had no adverse effects. It can prevent spread of infection in 24 hours. It is complementary to vaccination and can prevent infection from close contact. Next step is stage III trials for a bigger group of patients.

We are looking for investors to fund our next phase.
Website:
NA
Company Size (Fulltime employees)
Year of foundation
2019
Partnering Objectives
Please specify your partnering goal
We are raising money for phase III trials
Headquartner in China
Biotech/Pharma Category
Mr. David Platt
CEO 
Functionality

Bms United States

Pharmaceutical
Website:
N/a
Company Size (Fulltime employees)
Partnering Objectives
Please specify your partnering goal
N/a
Headquartner in China
Dr. Na Hu
Senior Manager 
Dr. Zhi Li
Manager 

Boston Scientific United States

Top American medical device company
Partnering Objectives
Headquartner in China
Biotech/Pharma Category
bingwen wang
physician